Description

3-([Pentafluorothio)Benzeneboronic acid, Pinacol ester is a high-purity, advanced organoboron building block designed for complex synthetic applications. This compound is valued for its unique combination of a boronic ester moiety and a pentafluorothio group, offering versatile reactivity for cross-coupling reactions and material science research. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds in pharmaceutical and agrochemical intermediates.
• Pharmaceutical Research: Used in the synthesis of complex molecules for drug discovery programs, particularly for candidates requiring fluorinated or sulfur-containing motifs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with enhanced properties.
• Material Science & OLEDs: Employed in the synthesis of advanced organic electronic materials, including charge-transport layers and emissive materials for OLED devices.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorochemical Research: Acts as a precursor for introducing the pentafluorothio (SF5) group, a highly lipophilic and electron-withdrawing bioisostere, into target molecules.

Basic Information

Product Name	3-([Pentafluorothio)Benzeneboronic acid, Pinacol ester
CAS No.	1286278-35-0
Molecular Formula	C12H12BF5O2S
Molecular Weight	310.10 g/mol
Synonyms	3-(Pentafluorosulfanyl)benzeneboronic acid pinacol ester; 3-(SF5)Phenylboronic Acid Pinacol Ester; (3-(Pentafluoro-λ6-sulfanyl)phenyl)boronic acid pinacol ester; 3-Pentafluorosulfanylphenylboronic Acid Pinacol Ester; Benzeneboronic acid, 3-(pentafluorothio)-, pinacol ester; 3-(SF5)C6H4Bpin; 3-(Pentafluorosulfanyl)phenylboronic Acid Neopentyl Glycol Ester (common alternative); B-(3-(Pentafluorosulfanyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-([Pentafluorothio)Benzeneboronic acid, Pinacol ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific project requirements, including custom purity grades for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.