Description

tert-Butyl (1R*,4R*)-4-(2-Bromobenzamido)Cyclohexylcarbamate is a sophisticated chiral organic intermediate featuring a brominated benzamide and a protected amine functionality. This compound is of significant value in pharmaceutical research and development, particularly for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for constructing novel drug candidates, especially those targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Protease Inhibitor Research: Used in the development of inhibitors for various protease enzymes, which are important targets in virology and oncology.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design of peptidomimetics to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective synthesis to introduce specific stereocenters.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	tert-Butyl (1R*,4R*)-4-(2-Bromobenzamido)Cyclohexylcarbamate
CAS No.	1286275-26-0
Molecular Formula	C18H25BrN2O3
Molecular Weight	397.31 g/mol
Synonyms	(1R,4R)-4-[[(2-Bromophenyl)carbonyl]amino]cyclohexyl carbamic acid 1,1-dimethylethyl ester; tert-Butyl N-[(1R,4R)-4-[(2-bromobenzoyl)amino]cyclohexyl]carbamate; (1R,4R)-N-(tert-Butoxycarbonyl)-4-(2-bromobenzamido)cyclohexylamine; Boc-(1R,4R)-4-(2-Bromobenzamido)cyclohexylamine; (1R,4R)-4-(2-Bromobenzamido)cyclohexyl carbamate tert-butyl ester; 2-Bromo-N-[(1R,4R)-4-[(tert-butoxycarbonyl)amino]cyclohexyl]benzamide
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (1R*,4R*)-4-(2-Bromobenzamido)Cyclohexylcarbamate is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a desiccated environment to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.