Description

tert-Butyl (1R*,4R*)-4-(Isobutylamino)Cyclohexylcarbamate is a specialized chiral amine derivative and carbamate-protected intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals, where precise stereochemistry and functional group manipulation are critical. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The carbamate-protected amine functionality makes it valuable for constructing peptide analogs and other bioactive molecules.
• Custom Synthesis & Contract Manufacturing: A high-purity starting material for custom chemical synthesis projects requiring specific stereochemical configurations.

Basic Information

Product Name	tert-Butyl (1R*,4R*)-4-(Isobutylamino)Cyclohexylcarbamate
CAS No.	1286273-53-7
Molecular Formula	C15H30N2O2
Molecular Weight	270.42 g/mol
Synonyms	N-(trans-4-((tert-Butoxycarbonyl)amino)cyclohexyl)-2-methylpropan-1-amine; (1R,4R)-4-((tert-Butoxycarbonyl)amino)cyclohexyl isobutylamine; tert-Butyl N-[(1R,4R)-4-(isobutylamino)cyclohexyl]carbamate; trans-4-(tert-Butoxycarbonylamino)cyclohexyl isobutylamine; Boc-trans-4-(isobutylamino)cyclohexylamine; (1R*,4R*)-tert-Butyl 4-(isobutylamino)cyclohexylcarbamate; CAS 1286273-53-7
EINECS	Contact for details

Quality Control

Our tert-Butyl (1R*,4R*)-4-(Isobutylamino)Cyclohexylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. For long-term storage, consider storing under nitrogen in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.