Description

tert-Butyl (1R*,4R*)-4-(3-Cyanobenzylamino)Cyclohexylcarbamate is a sophisticated chiral building block and pharmaceutical intermediate of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on enantioselective synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the (1R*,4R*) cyclohexylamine moiety into target molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetics & Bioactive Molecule Synthesis: Used in the construction of non-peptide compounds designed to mimic peptide function, leveraging its carbamate and benzylamino functional groups.
• Agrochemical Intermediate: Potential application in the synthesis of advanced, chiral active ingredients for crop protection products.
• Catalyst & Ligand Development: Can be employed as a precursor for creating novel chiral ligands or organocatalysts used in enantioselective transformations.

Basic Information

Product Name	tert-Butyl (1R*,4R*)-4-(3-Cyanobenzylamino)Cyclohexylcarbamate
CAS No.	1286273-01-5
Molecular Formula	C19H27N3O2
Molecular Weight	329.44 g/mol
Synonyms	tert-Butyl N-[(1R*,4R*)-4-[[(3-Cyanophenyl)methyl]amino]cyclohexyl]carbamate; (1R*,4R*)-4-[(3-Cyanobenzyl)amino]cyclohexylcarbamic Acid tert-Butyl Ester; 1,1-Dimethylethyl N-[(1R*,4R*)-4-[[(3-cyanophenyl)methyl]amino]cyclohexyl]carbamate; 1286273-01-5; tert-Butyl (1R,4R)-4-((3-cyanobenzyl)amino)cyclohexylcarbamate (relative stereochemistry); 4-[(3-Cyanobenzyl)amino]cyclohexylcarbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (1R*,4R*)-4-(3-Cyanobenzylamino)Cyclohexylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.