Description

tert-Butyl 1-(2-Cyanobenzoyl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine carbamate structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Key Intermediate in API Synthesis: Serves as a critical building block in the multi-step synthesis of complex drug candidates, especially those containing a piperidine moiety.
• Medicinal Chemistry Research: Used extensively in research and development (R&D) laboratories for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological screening, toxicology studies, and early-stage clinical trial material.
• Neurological & Psychiatric Drug Discovery: Particularly relevant for developing potential treatments for conditions such as depression, anxiety, and cognitive disorders.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	tert-Butyl 1-(2-Cyanobenzoyl)Piperidin-4-Ylcarbamate
CAS No.	1286272-85-2
Molecular Formula	C18H23N3O3
Molecular Weight	329.40 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(2-cyanobenzoyl)piperidine; 1-(2-Cyanobenzoyl)-4-[(tert-butoxycarbonyl)amino]piperidine; tert-Butyl N-[1-(2-cyanobenzoyl)piperidin-4-yl]carbamate; Boc-4-Amino-1-(2-cyanobenzoyl)piperidine; 4-(Boc-amino)-1-(2-cyanobenzoyl)piperidine; Piperidine-4-carbamic acid, 1-(2-cyanobenzoyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(2-Cyanobenzoyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.