Description

tert-Butyl 1-(2-Fluoro-5-Methylbenzyl)Piperidin-4-Ylcarbamate CAS NO 1286265-39-1 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex drug molecules.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of proprietary compounds for clients.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	tert-Butyl 1-(2-Fluoro-5-Methylbenzyl)Piperidin-4-Ylcarbamate
CAS No.	1286265-39-1
Molecular Formula	C18H27FN2O2
Molecular Weight	322.42 g/mol
Synonyms	1-(2-Fluoro-5-methylbenzyl)piperidin-4-amine, N-Boc derivative; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[(2-fluoro-5-methylphenyl)methyl]piperidine; tert-Butyl N-[1-[(2-fluoro-5-methylphenyl)methyl]piperidin-4-yl]carbamate; 1-(2-Fluoro-5-methylbenzyl)piperidin-4-yl-carbamic acid tert-butyl ester; Boc-4-amino-1-(2-fluoro-5-methylbenzyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(2-Fluoro-5-Methylbenzyl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.