Description

tert-Butyl (1R*,4R*)-4-Propionamidocyclohexylcarbamate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories focused on creating novel therapeutic agents, including potential candidates for central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for complex small-molecule drugs.
• Peptidomimetic Research: Serves as a constrained scaffold or backbone component in the design and synthesis of peptidomimetics and protease inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective reactions to introduce defined stereochemistry into target molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl (1R*,4R*)-4-Propionamidocyclohexylcarbamate
CAS No.	1286264-07-0
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	tert-Butyl N-[(1R,4R)-4-propionamidocyclohexyl]carbamate; (1R,4R)-4-[(tert-Butoxycarbonyl)amino]cyclohexanepropionamide; (1R,4R)-N-(tert-Butoxycarbonyl)-4-aminocyclohexanepropionamide; tert-Butyl (1R,4R)-4-(propionylamino)cyclohexylcarbamate; (1R,4R)-4-Aminocyclohexanepropionamide, N-BOC-protected; Boc-(1R,4R)-4-Aminocyclohexylpropionamide; CAS 1286264-07-0
EINECS	Contact for details

Quality Control

Our tert-Butyl (1R*,4R*)-4-Propionamidocyclohexylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.