Description

tert-Butyl [(1-Cyclobutylpiperidin-4-Yl)Methyl]Carbamate CAS NO 1286263-52-2 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a cyclobutyl substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• API Synthesis: Employed in the development and scale-up of novel Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Biology Probes: Serves as a building block for creating specialized molecular probes to study biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	tert-Butyl [(1-Cyclobutylpiperidin-4-Yl)Methyl]Carbamate
CAS No.	1286263-52-2
Molecular Formula	C15H28N2O2
Molecular Weight	268.40 g/mol
Synonyms	Boc-4-(aminomethyl)-1-cyclobutylpiperidine; 1,1-Dimethylethyl N-[[1-(cyclobutyl)-4-piperidinyl]methyl]carbamate; tert-Butyl N-[(1-cyclobutylpiperidin-4-yl)methyl]carbamate; 4-(Boc-aminomethyl)-1-cyclobutylpiperidine; 1-Cyclobutyl-4-[(tert-butoxycarbonylamino)methyl]piperidine; (1-Cyclobutylpiperidin-4-yl)methyl carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1-Cyclobutylpiperidin-4-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.