Description

(R)-tert-Butyl 1-Benzoylpyrrolidin-3-Ylcarbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its core value lies in providing a stereochemically defined pyrrolidine scaffold, which is a privileged structure in drug discovery for creating active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the development of novel therapeutics targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, especially those containing a substituted pyrrolidine moiety.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds for medicinal chemistry research and development.
• Protease Inhibitor Research: Serves as a precursor in the development of inhibitors for various enzymes, including dipeptidyl peptidase-4 (DPP-4).
• Chemical Biology: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Process Chemistry: Utilized in route scouting and scale-up optimization for the commercial manufacturing of advanced pharmaceutical intermediates.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	(R)-tert-Butyl 1-Benzoylpyrrolidin-3-Ylcarbamate
CAS No.	1286208-93-2
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	(R)-1-Benzoyl-3-((tert-butoxycarbonyl)amino)pyrrolidine; (R)-N-Boc-1-benzoylpyrrolidin-3-amine; tert-Butyl N-[(3R)-1-benzoylpyrrolidin-3-yl]carbamate; (R)-tert-Butyl (1-benzoylpyrrolidin-3-yl)carbamate; (3R)-1-Benzoyl-N-(tert-butoxycarbonyl)pyrrolidin-3-amine; (R)-3-((tert-Butoxycarbonyl)amino)-1-benzoylpyrrolidine; BOC-(R)-1-Benzoylpyrrolidin-3-ylamine
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-Benzoylpyrrolidin-3-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.