Description

(R)-tert-Butyl 1-Neopentylpyrrolidin-3-Ylcarbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, process chemistry, and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds for medicinal chemistry research and development.
• Process Chemistry: Serves as a key starting material or intermediate in scale-up and optimization studies for drug manufacturing.
• Neurological Research: Employed in the development of compounds targeting neurological pathways and receptors.
• Custom Synthesis: A substrate for the preparation of more complex, functionalized pyrrolidine derivatives.
• Catalyst & Ligand Development: Potential use in the synthesis of novel chiral catalysts or ligands for organic transformations.

Basic Information

Product Name	(R)-tert-Butyl 1-Neopentylpyrrolidin-3-Ylcarbamate
CAS No.	1286208-50-1
Molecular Formula	C14H28N2O2
Molecular Weight	256.39 g/mol
Synonyms	tert-Butyl (3R)-1-(2,2-dimethylpropyl)pyrrolidin-3-ylcarbamate; (R)-1-Neopentyl-3-((tert-butoxycarbonyl)amino)pyrrolidine; (R)-N-Boc-1-neopentyl-3-aminopyrrolidine; (R)-1-(2,2-Dimethylpropyl)-3-((tert-butoxycarbonyl)amino)pyrrolidine; BOC-(R)-1-Neopentyl-3-aminopyrrolidine; (R)-1-Neopentylpyrrolidin-3-amine, N-BOC derivative
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 1-Neopentylpyrrolidin-3-Ylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.