Description

(R)-n-(Piperidin-3-Yl)Isobutyramide Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and oncology. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in asymmetric synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with defined stereochemistry in medicinal chemistry programs.
• Research & Development: Serves as a reference standard and starting material in academic and industrial research for investigating new therapeutic pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for advanced pharmaceutical intermediates.
• Ligand & Catalyst Development: Potential precursor for creating chiral ligands or organocatalysts used in enantioselective transformations.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological targets and mechanisms.

Basic Information

Product Name	(R)-n-(Piperidin-3-Yl)Isobutyramide Hydrochloride
CAS No.	1286207-24-6
Molecular Formula	C9H19ClN2O
Molecular Weight	206.72 g/mol
Synonyms	(R)-N-(Piperidin-3-yl)-2-methylpropanamide hydrochloride; (R)-3-(2-Methylpropanamido)piperidine hydrochloride; (R)-Isobutyryl-3-aminopiperidine hydrochloride; (R)-Tert-Leucinamide piperidine analog hydrochloride; (3R)-N-(Piperidin-3-yl)-2-methylpropanamide hydrochloride; (R)-Piperidin-3-yl-isobutyramide HCl; UNII-Contact for details; (R)-3-Isobutyramidopiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-n-(Piperidin-3-Yl)Isobutyramide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.