Description

3-((1S,3S)-Adamantan-1-Yl)-n-((E)-4-Fluorobenzylidene)-1H-Pyrazole-5-Carbohydrazide is a high-purity, structurally complex organic compound featuring adamantane and fluorinated aromatic pharmacophores. This compound is of significant interest for its potential as a key intermediate or active scaffold in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in areas requiring molecules with specific stereochemistry and fluorinated motifs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing antiviral properties.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic profiles.
• Biochemical Tool Compound: Employed in in-vitro assays to investigate specific biological pathways or protein interactions.
• Reference Standard: Provides a high-purity standard for analytical method development and validation in quality control laboratories.
• Organic Synthesis: Acts as a specialized reagent for constructing complex molecular architectures containing the adamantyl group and fluorinated benzene rings.

Basic Information

Item	Details
Product Name	3-((1S,3S)-Adamantan-1-Yl)-n-((E)-4-Fluorobenzylidene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1285650-36-3
Molecular Formula	C21H23FN4O
Molecular Weight	366.44 g/mol
Synonyms	(1S,3S)-1-(5-((E)-2-(4-Fluorobenzylidene)hydrazinecarbonyl)-1H-pyrazol-3-yl)adamantane; 3-((1S,3S)-Adamantan-1-yl)-1H-pyrazole-5-carboxylic acid (E)-2-(4-fluorobenzylidene)hydrazide; (E)-N'-(4-Fluorobenzylidene)-3-((1S,3S)-adamantan-1-yl)-1H-pyrazole-5-carbohydrazide; 3-(Adamantan-1-yl)-N-((E)-4-fluorobenzylidene)-1H-pyrazole-5-carbohydrazide (stereoisomer); Adamantyl pyrazole carbohydrazide derivative; 4-Fluorobenzylidene adamantylpyrazole carbohydrazone
EINECS	Contact for details

Quality Control

Our 3-((1S,3S)-Adamantan-1-Yl)-n-((E)-4-Fluorobenzylidene)-1H-Pyrazole-5-Carbohydrazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.