Description

(E)-n-(2-Hydroxy-3-Methoxybenzylidene)-3-(Thiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide is a high-purity, advanced organic intermediate characterized by its Schiff base and heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, high-value chemical entities, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or anti-inflammatory pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic framework for bioactivity.
• Coordination Chemistry & Ligand Synthesis: Acts as a versatile ligand for metal complexation, useful in catalysis and material science applications.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic systems and fine chemicals.
• Material Science Research: Investigated for the development of organic semiconductors, sensors, or non-linear optical materials due to its conjugated structure.

Basic Information

Product Name	(E)-n-(2-Hydroxy-3-Methoxybenzylidene)-3-(Thiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1285536-79-9
Molecular Formula	C₁₇H₁₄N₄O₃S
Molecular Weight	354.38 g/mol
Synonyms	(E)-N'-(2-Hydroxy-3-methoxybenzylidene)-3-(thiophen-2-yl)-1H-pyrazole-5-carbohydrazide; 3-(2-Thienyl)-1H-pyrazole-5-carboxylic acid, 2-[(2-hydroxy-3-methoxyphenyl)methylene]hydrazide; (E)-2-((2-Hydroxy-3-methoxybenzylidene)hydrazineylidene)-3-(thiophen-2-yl)-2,3-dihydro-1H-pyrazole-5-carboxamide; 3-(Thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (2-hydroxy-3-methoxybenzylidene)hydrazide; Pyrazole-thiophene Schiff base derivative; Light-sensitive pyrazole carbohydrazide.
EINECS	Contact for details

Quality Control

Our (E)-n-(2-Hydroxy-3-Methoxybenzylidene)-3-(Thiophen-2-Yl)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.