Description

2-(1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxamido)-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid is a sophisticated bifunctional organic compound that serves as a critical building block in advanced chemical synthesis. Its molecular architecture, featuring both a protected pyrrolidine moiety and a biphenyl dicarboxylic acid core, makes it an invaluable intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in the creation of novel active pharmaceutical ingredients (APIs), specialty polymers, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Used to incorporate constrained, proline-like structures into peptide backbones to enhance stability and bioavailability.
• Ligand Synthesis for Catalysis: Serves as a starting material for creating chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Polymer Chemistry: Functions as a monomer or cross-linking agent for developing high-performance, functionalized polymers and polyamides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Material Science: Employed in the development of organic semiconductors and liquid crystalline materials due to its rigid biphenyl core.

Basic Information

Item	Detail
Product Name	2-(1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxamido)-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid
CAS No.	1283676-82-3
Molecular Formula	C25H28N2O7
Molecular Weight	468.50 g/mol
Synonyms	Boc-Pro-Biphenyl-4,4'-dicarboxylic Acid; 4,4'-Biphenyldicarboxylic Acid, 2-[(1-[[(1,1-Dimethylethoxy)carbonyl]-2-pyrrolidinyl]carbonyl]amino]-; 2-[(1-Boc-pyrrolidine-2-carboxamido)]-[1,1'-biphenyl]-4,4'-dicarboxylic Acid; N-(1-Boc-pyrrolidine-2-carbonyl)-[1,1'-biphenyl]-4,4'-dicarboxylic Acid Amide; Biphenyl-4,4'-dicarboxylic Acid Derivative; CAS 1283676-82-3
EINECS	Contact for details

Quality Control

Every batch of 2-(1-(tert-Butoxycarbonyl)Pyrrolidine-2-Carboxamido)-[1,1'-Biphenyl]-4,4'-Dicarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under dry, inert conditions to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.