Description

Sodium2,2-Difluoropropionate CAS NO 1281943-34-7 is a high-purity, organofluorine building block and salt derivative of 2,2-difluoropropionic acid. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides where fluorine substitution improves efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for fluorinated ligands used in asymmetric catalysis and material science.
• Organic Synthesis Reagent: Employed in various fluorination reactions and as a source of the difluoromethyl (CF2) moiety in complex organic molecules.
• Material Science Research: Investigated for the development of fluorinated polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying biological mechanisms and diagnostics.

Basic Information

Item	Detail
Product Name	Sodium 2,2-Difluoropropionate
CAS No.	1281943-34-7
Molecular Formula	C3H3F2NaO2
Molecular Weight	132.04 g/mol
Synonyms	Sodium 2,2-Difluoropropanoate; 2,2-Difluoropropionic Acid Sodium Salt; Sodium α,α-Difluoropropionate; Propanoic acid, 2,2-difluoro-, sodium salt (1:1); DFPA Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium 2,2-Difluoropropionate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.