Description

[1-(2,3-Dihydro-Benzo[1,4]Dioxine-2-Carbonyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry Development: Serves as a critical intermediate for scaling up API manufacturing processes under GMP conditions.
• Custom Synthesis: A starting material for the custom synthesis of specialized compounds for biological screening and testing.
• Reference Standard: High-purity material suitable for use as an analytical reference standard in quality control laboratories.

Basic Information

Product Name	[1-(2,3-Dihydro-Benzo[1,4]Dioxine-2-Carbonyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1280871-11-5
Molecular Formula	C19H26N2O5
Molecular Weight	362.42 g/mol
Synonyms	1-(2,3-Dihydro-1,4-benzodioxin-2-carbonyl)-4-[(tert-butoxycarbonyl)amino]piperidine; tert-Butyl N-[1-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperidin-4-yl]carbamate; 1,4-Benzodioxan-2-carbonyl-piperidin-4-yl-carbamic acid tert-butyl ester; 4-[(tert-Butoxycarbonyl)amino]-1-(1,4-benzodioxan-2-carbonyl)piperidine; BOC-Piperidine-1,4-benzodioxane carboxamide; 1280871-11-5; UNII-9S6B1T8I4F
EINECS	Contact for details

Quality Control

Our [1-(2,3-Dihydro-Benzo[1,4]Dioxine-2-Carbonyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.