Description

4-(N,N-Dimethylsulfamoyl)-2-Trifluoromethylphenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative that serves as a critical building block in modern organic synthesis. Its molecular structure, featuring both a boronic acid group and a dimethylsulfamoyl moiety, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced materials. Its reliable performance and consistent quality are vital for ensuring the success and reproducibility of complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Serves as a building block for synthesizing molecular probes and inhibitors used to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.
• Academic Research: A valuable reagent in university and institutional labs for methodological development in organoboron chemistry and catalysis.

Basic Information

Product Name	4-(N,N-Dimethylsulfamoyl)-2-Trifluoromethylphenylboronic Acid
CAS No.	1279107-82-2
Molecular Formula	C9H11BF3NO4S
Molecular Weight	297.06 g/mol
Synonyms	[4-(Dimethylsulfamoyl)-2-(trifluoromethyl)phenyl]boronic Acid; 2-Trifluoromethyl-4-(N,N-dimethylsulfamoyl)phenylboronic Acid; 4-(Dimethylsulfamoyl)-2-(trifluoromethyl)benzeneboronic Acid; B-[4-(Dimethylsulfamoyl)-2-(trifluoromethyl)phenyl]boronic Acid; 4-(N,N-Dimethylsulfamoyl)-2-trifluoromethylbenzeneboronic Acid; (4-(Dimethylsulfamoyl)-2-(trifluoromethyl)phenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. We adhere to strict in-house specifications designed to meet the demands of pharmaceutical R&D. Certificates of Analysis (COA) are available upon request and provide full traceability and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.