Description

Nelfinavir-D3 CAS NO 1279035-85-6 is a deuterated analog of the antiretroviral drug Nelfinavir, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative bioanalytical methods, ensuring the highest accuracy and reliability in pharmacokinetic and metabolic studies. It is a critical tool for pharmaceutical researchers, contract research organizations (CROs), and analytical laboratories developing and validating LC-MS/MS assays for antiviral drug monitoring and research.

Application

• Primary use as an internal standard for the precise quantification of Nelfinavir in biological matrices (e.g., plasma, serum) via LC-MS/MS.
• Metabolite identification and drug metabolism and pharmacokinetics (DMPK) studies in preclinical and clinical research.
• Supporting bioequivalence and bioavailability studies for generic drug development.
• Use in forensic and clinical toxicology for accurate measurement of drug concentrations.
• Method development and validation in contract research organizations (CROs) and analytical service labs.
• Quality control and assurance in pharmaceutical manufacturing processes involving protease inhibitors.

Basic Information

Product Name	Nelfinavir-D3
CAS No.	1279035-85-6
Molecular Formula	C32H42D3N3O4S
Molecular Weight	570.80 g/mol (approximate)
Synonyms	Nelfinavir-d3; [2S-[2R*(R*),3S*]]-N-(3-[(1,1-Dimethylethyl)amino]-2-hydroxy-4-phenylbutyl)-Nα-methyl-Nα-(2-methylpropyl)-3-[(2-quinolinylcarbonyl)amino]-butanediamide-d3; AG1343-d3; Viracept-d3; Deuterated Nelfinavir; Nelfinavir Internal Standard
EINECS	Contact for details

Quality Control

Our Nelfinavir-D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and purity by HPLC. We adhere to relevant GMP guidelines for the production of reference standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.