Description

Fmoc-o-Methyl-D-Ser CAS NO 1279032-69-7 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is specifically engineered to provide superior chiral integrity and stability during solid-phase and solution-phase coupling reactions. It is a critical building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of O-methyl-D-serine into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and peptidomimetics requiring precise stereochemistry.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of active pharmaceutical ingredients (APIs) for metabolic, oncological, and neurological disorders.
• Bioconjugation and Labeling: Facilitates the site-specific modification of peptides for creating targeted drug conjugates or diagnostic probes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptide leads.
• Academic and Industrial R&D: Used in studies exploring protein structure-function relationships, enzyme substrates, and receptor ligands.

Basic Information

Product Name	Fmoc-o-Methyl-D-Ser
CAS No.	1279032-69-7
Molecular Formula	C19H19NO5
Molecular Weight	341.36 g/mol
Synonyms	Fmoc-O-Me-D-Ser-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-D-serine; Fmoc-D-Ser(OMe)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxypropanoic acid; Fmoc-D-O-Methylserine; N-Fmoc-O-methyl-D-serine; Fmoc-D-Ser(Me)-OH; D-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ether
EINECS	Contact for details

Quality Control

Our Fmoc-o-Methyl-D-Ser is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically exceeding 98.0% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates, ensuring material suitability for advanced research and GMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.