Description

Carmoterol-D3 Hydrochloride is a deuterium-labeled analog of the β-2 adrenergic receptor agonist Carmoterol, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity reference material is essential for ensuring accuracy and reliability in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities involved in drug development and bioanalysis.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Carmoterol in complex biological matrices such as plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profile of Carmoterol.
• Bioanalytical Method Development and Validation: Serves as a stable isotope-labeled standard to improve method robustness, accuracy, and to correct for matrix effects and instrument variability.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Supports the analysis of drug concentrations in patient samples during clinical trials.
• Pharmaceutical Quality Control: Can be employed in impurity profiling and stability-indicating assay methods for Carmoterol-based drug products.
• Forensic and Anti-Doping Analysis: Facilitates the definitive identification and quantification of the parent compound in specialized testing scenarios.

Basic Information

Product Name	Carmoterol-D3 Hydrochloride
CAS No.	1276319-69-7
Molecular Formula	C19H21D3N2O4 • HCl
Molecular Weight	Contact for details
Synonyms	8-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone-d3 hydrochloride; (R,R)-Formoterol-d3 hydrochloride; Carmoterol-d3 HCl; BI-1744-CL-d3 hydrochloride; 5-[(1R)-1-Hydroxy-2-{[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl]-8-hydroxyquinolin-2(1H)-one-d3 hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Carmoterol-D3 Hydrochloride is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, confirmed by advanced spectroscopic and chromatographic techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results for identity, purity, and deuterium enrichment. Our quality commitment ensures reliability for your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.