Description

Sodium 17β-Dihydroequilenin-4,16,16-D3 3-Sulfate is a high-purity, deuterium-labeled steroid sulfate salt used as a critical reference standard and analytical reagent. This compound matters for its role in ensuring the accuracy and reliability of quantitative bioanalytical methods, particularly in regulated environments. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and diagnostic manufacturers working on hormone analysis, metabolism studies, and pharmacokinetic research.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard for the precise quantification of equine estrogens and related metabolites in biological matrices.
• Pharmaceutical R&D: Supports method development and validation for bioequivalence studies and clinical trials involving hormone-based therapies.
• Metabolite Profiling: Aids in the identification and quantification of specific sulfated steroid metabolites in metabolic pathway research.
• Diagnostic Assay Development: Serves as a calibrant or control material in the development of high-sensitivity diagnostic tests for endocrine function.
• Regulatory Compliance Testing: Essential for laboratories requiring traceable and certified reference materials to meet FDA, EMA, or other regulatory guidelines for data integrity.
• Forensic Toxicology: Can be employed in specialized forensic analyses for the detection of synthetic or natural steroids.

Basic Information

Product Name	Sodium 17β-Dihydroequilenin-4,16,16-D3 3-Sulfate
CAS No.	1276056-91-7
Molecular Formula	C18H17D3NaO5S
Molecular Weight	Contact for details
Synonyms	Sodium 17β-Dihydroequilenin-4,16,16-d3 3-Sulfate; 17β-Dihydroequilenin-4,16,16-d3 3-Sulfate Sodium Salt; [4,16,16-2H3]-17β-Dihydroequilenin 3-Sulfate Sodium Salt; Deuterated Sodium Equilenin Sulfate; 3-Sulfooxyestra-1,3,5(10),6,8-pentaen-17-ol-4,16,16-d3 Sodium Salt; Sodium 17β-Dihydroequilin-4,16,16-d3 Sulfate (related); Stable Isotope-Labeled Estrogen Sulfate.
EINECS	Contact for details

Quality Control

Every batch of Sodium 17β-Dihydroequilenin-4,16,16-D3 3-Sulfate is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to support its use as a reference standard, including confirmation of isotopic purity and chemical purity via advanced chromatographic and spectroscopic techniques. A detailed Certificate of Analysis (COA) is supplied with each shipment, providing batch-specific results for identity, purity (HPLC), isotopic enrichment (MS), and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.