Description

17β-Dihydroequilenin-4,16,16-D3 is a deuterium-labeled derivative of the natural estrogenic steroid equilenin. This compound is specifically designed for use as a high-purity internal standard in analytical chemistry, enabling precise quantification and method validation. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors who require accurate and reliable mass spectrometry-based analyses, such as LC-MS/MS, for hormone-related studies and bioanalytical assays.

Application

• Primary use as a stable isotope-labeled internal standard for quantitative mass spectrometry (LC-MS/MS, GC-MS).
• Method development and validation for the analysis of equine estrogens and related metabolites in biological matrices.
• Pharmacokinetic and pharmacodynamic studies in pharmaceutical research and development.
• Quality control and assurance testing in the manufacturing of steroid-based active pharmaceutical ingredients (APIs).
• Clinical research applications investigating hormone metabolism and endocrine pathways.
• Supporting regulatory submissions by providing definitive analytical reference data.

Basic Information

Product Name	17β-Dihydroequilenin-4,16,16-D3
CAS No.	1276056-90-6
Molecular Formula	C18H15D3O2
Molecular Weight	269.36 g/mol (approx.)
Synonyms	17β-Dihydroequilenin-4,16,16-d3; 17β-Dihydroequilenin-d3; 13,14-Dihydroequilenin-4,16,16-d3; 13,14-Dihydro-17β-equilenin-d3; Equilenin-4,16,16-d3 derivative; Deuterated 17β-dihydroequilenin; [4,16,16-D3]-17β-Dihydroequilenin; Isotopically labeled equilenin metabolite.
EINECS	Contact for details

Quality Control

Our 17β-Dihydroequilenin-4,16,16-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isotopic enrichment verification by mass spectrometry, to ensure it meets the high standards required for use as a certified reference material. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, chemical purity, and isotopic purity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chemical Purity	≥ 95.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.