Description

Bzl,Me-L-Val-Ome Hcl is a protected amino acid derivative, specifically a benzyl-methyl ester of L-valine hydrochloride. This compound is a crucial chiral building block in the synthesis of complex peptides and pharmaceutical intermediates, offering precise control over stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce the valine residue with orthogonal protecting groups.
• Bioconjugation: Serves as a linker or modifying agent in the creation of antibody-drug conjugates (ADCs) and other bioconjugates.
• Proteomics Research: Employed in biochemical research for studying enzyme-substrate interactions and protein structure-function relationships.
• Fine Chemical Synthesis: Acts as a building block for non-peptidic compounds requiring a specific chiral valine moiety.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and process development in both academic and industrial laboratories.

Basic Information

Item	Details
Product Name	Bzl,Me-L-Val-Ome Hcl
CAS No.	1272755-73-3
Molecular Formula	C14H21NO3 • HCl
Molecular Weight	287.78 g/mol
Synonyms	N-Benzyloxycarbonyl-N-methyl-L-valine methyl ester hydrochloride; Z-Me-Val-OMe • HCl; Cbz-N-methyl-L-valine methyl ester hydrochloride; (2S)-3-Methyl-2-[(phenylmethoxy)carbonyl-methyl-amino]butanoic acid methyl ester hydrochloride; N-Carbobenzyloxy-N-methyl-L-valine methyl ester hydrochloride; Bzl-Me-Val-OMe HCl; Nα-Cbz-Nα-methyl-L-valine methyl ester hydrochloride; N-Benzyloxycarbonyl-N-methylvaline methyl ester HCl
EINECS	Contact for details

Quality Control

Our Bzl,Me-L-Val-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.