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(+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenylphosphine, Min. 98% [Catasiumt2] CAS NO 1272755-16-4
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CAS No.:1272755-16-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenyl)phosphine, Min. 98% is a high-purity, chiral phosphine ligand, also known as Catasiumt2, designed for advanced asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the synthesis of complex chiral molecules. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for process development and scale-up.
Application
- As a privileged ligand in asymmetric hydrogenation reactions for the synthesis of chiral amines, amino acids, and alcohols.
- Catalyst component for enantioselective cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
- Key chiral inducer in asymmetric allylic substitution and hydrofunctionalization processes.
- Critical reagent in pharmaceutical intermediate manufacturing for active pharmaceutical ingredients (APIs).
- Use in agrochemical research for the development of enantiomerically pure herbicides and fungicides.
- Facilitation of academic and industrial R&D in novel catalytic methodologies and total synthesis.
- Production of specialty and performance chemicals requiring precise stereochemical control.
Basic Information
| Item | Details |
|---|---|
| Product Name | (+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenyl)phosphine, Min. 98% |
| CAS No. | 1272755-16-4 |
| Molecular Formula | C51H56P3S |
| Molecular Weight | 785.00 g/mol |
| Synonyms | Catasiumt2; (1S,4R)-3-[4-(Diphenylphosphino)-2,5-dimethyl-3-thienyl]-4,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-ylbis(3,5-dimethylphenyl)phosphine; (S,R)-Catasiumt2; (1S,4R)-Catasiumt2; (+)-Catasiumt2 ligand; Chiral phosphine ligand Catasiumt2; Asymmetric hydrogenation ligand T2. |
| EINECS | Contact for details |
Quality Control
Our Catasiumt2 ligand is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and chiral analysis, to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The container should be kept in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | Min. 98.0% |
| Chiral Purity (HPLC) | Min. 99.0% e.e. |
| Water Content (KF) | Max. 0.5% |
| Residue on Ignition | Max. 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






