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(+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenylphosphine, Min. 98% [Catasiumt2] CAS NO 1272755-16-4


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CAS No.:1272755-16-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenyl)phosphine, Min. 98% is a high-purity, chiral phosphine ligand, also known as Catasiumt2, designed for advanced asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, enabling the synthesis of complex chiral molecules. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for process development and scale-up.

Application

  • As a privileged ligand in asymmetric hydrogenation reactions for the synthesis of chiral amines, amino acids, and alcohols.
  • Catalyst component for enantioselective cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
  • Key chiral inducer in asymmetric allylic substitution and hydrofunctionalization processes.
  • Critical reagent in pharmaceutical intermediate manufacturing for active pharmaceutical ingredients (APIs).
  • Use in agrochemical research for the development of enantiomerically pure herbicides and fungicides.
  • Facilitation of academic and industrial R&D in novel catalytic methodologies and total synthesis.
  • Production of specialty and performance chemicals requiring precise stereochemical control.

Basic Information

Item Details
Product Name (+)-{(1S,4R)-3-[4-(Diphenylphosphino)-2,5-Dimethyl-3-Thienyl]-4, 7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}Bis(3,5-Dimethylphenyl)phosphine, Min. 98%
CAS No. 1272755-16-4
Molecular Formula C51H56P3S
Molecular Weight 785.00 g/mol
Synonyms Catasiumt2; (1S,4R)-3-[4-(Diphenylphosphino)-2,5-dimethyl-3-thienyl]-4,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-ylbis(3,5-dimethylphenyl)phosphine; (S,R)-Catasiumt2; (1S,4R)-Catasiumt2; (+)-Catasiumt2 ligand; Chiral phosphine ligand Catasiumt2; Asymmetric hydrogenation ligand T2.
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Quality Control

Our Catasiumt2 ligand is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and chiral analysis, to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The container should be kept in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) Min. 98.0%
Chiral Purity (HPLC) Min. 99.0% e.e.
Water Content (KF) Max. 0.5%
Residue on Ignition Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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