Description

1-Methoxy-3-(Pentafluorosulfanyl)Benzene is a high-value fluorinated aromatic building block, distinguished by the unique pentafluorosulfanyl (SF₅) functional group. This compound is prized for its exceptional combination of high lipophilicity, thermal stability, and strong electron-withdrawing properties, making it a critical intermediate in advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly where metabolic stability and bioavailability enhancement are required.
• Agrochemical Synthesis: Serves as a key precursor for novel herbicides, fungicides, and insecticides, leveraging the SF₅ group to improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Incorporated into the design of advanced electronic materials for displays and lighting due to its influence on dielectric anisotropy and molecular alignment.
• Polymer & Material Science: Used to modify polymers, imparting specific properties like chemical resistance, low surface energy, or unique optical characteristics.
• Organic Synthesis Building Block: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the SF₅ moiety into complex molecular architectures.
• Positron Emission Tomography (PET) Tracer Development: Potential use in creating fluorine-18 labeled tracers for medical imaging, given the presence of multiple fluorine atoms.

Basic Information

Product Name	1-Methoxy-3-(Pentafluorosulfanyl)Benzene
CAS No.	1272542-23-0
Molecular Formula	C₇H₅F₅OS
Molecular Weight	232.17 g/mol
Synonyms	3-Methoxybenzenesulfonyl pentafluoride; 3-(Pentafluorosulfanyl)anisole; m-(Pentafluorosulfanyl)anisole; 1-Methoxy-3-(SF5)benzene; 3-Methoxyphenylsulfur pentafluoride; SF5-Anisole; Benzene, 1-methoxy-3-(pentafluorosulfanyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-Methoxy-3-(Pentafluorosulfanyl)Benzene is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR (¹H, ¹⁹F, ¹³C), and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.