Description

tert-Butyl n-(2-Amino-2-Cyclohexylethyl)Carbamate is a protected amino acid derivative, specifically a Boc-protected diamine, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, scalable building blocks for API synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Peptidomimetics & Constrained Peptide Synthesis: Used to introduce cyclohexylalanine-like motifs and rigidify peptide backbones to enhance metabolic stability and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Building block for creating advanced herbicides and fungicides with specific stereochemical requirements.
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRO/CMO) for bespoke chemical projects requiring a protected diamine functionality.
• Academic & Research Chemistry: A valuable reagent for methodology development and exploring new chemical spaces in university and institutional labs.

Basic Information

Product Name	tert-Butyl n-(2-Amino-2-Cyclohexylethyl)Carbamate
CAS No.	1270370-49-4
Molecular Formula	C₁₃H₂₆N₂O₂
Molecular Weight	242.36 g/mol
Synonyms	Boc-1,2-Diaminocyclohexylethane; N-Boc-1,2-Diamino-2-cyclohexylethane; 2-((tert-Butoxycarbonyl)amino)-2-cyclohexylethan-1-amine; tert-Butyl (2-amino-2-cyclohexylethyl)carbamate; 1,2-Ethanediamine, N1-[(1,1-dimethylethoxy)carbonyl]-2-cyclohexyl-; (2-Amino-2-cyclohexylethyl)carbamic acid tert-butyl ester; Boc-Cyclohexylalanine amide derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2-Amino-2-Cyclohexylethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.