Description

5-Fluoro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carbonitrile is a high-purity, heterocyclic organic compound designed for advanced chemical synthesis. This specialized intermediate is critical for research and development in the pharmaceutical and agrochemical sectors, where precise molecular architecture is paramount. It is primarily sought after by R&D chemists and process development scientists for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Employed in the research of advanced organic electronic materials and coordination polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex pyrazole-pyrimidine hybrids.

Basic Information

Product Name	5-Fluoro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carbonitrile
CAS No.	1269291-01-1
Molecular Formula	C8H4FN5
Molecular Weight	189.15 g/mol
Synonyms	5-Fluoro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile; 1H-Pyrazole-4-carbonitrile, 5-fluoro-1-(2-pyrimidinyl)-; 1269291-01-1; 5-Fluoro-1-(2-pyrimidinyl)-1H-pyrazole-4-carbonitrile; 5-Fluoro-1-pyrimidin-2-yl-1H-pyrazole-4-carbonitrile; 5-Fluoro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile; 5-Fluoro-1-(2-pyrimidinyl)-1H-pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.