Description

3-(Trifluoromethyl)Oxolan-3-Ol is a high-value fluorinated heterocyclic building block. This compound is critical for introducing the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the CF3 group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals with unique electronic and surface properties.
• Organic Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	3-(Trifluoromethyl)Oxolan-3-Ol
CAS No.	1269151-92-9
Molecular Formula	C5H7F3O2
Molecular Weight	156.10 g/mol
Synonyms	3-(Trifluoromethyl)tetrahydrofuran-3-ol; 3-Hydroxy-3-(trifluoromethyl)tetrahydrofuran; 3-Trifluoromethyloxolan-3-ol; 3-Trifluoromethyltetrahydrofuran-3-ol; Oxolan-3-ol, 3-(trifluoromethyl)-; Tetrahydro-3-(trifluoromethyl)-3-furanol
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Oxolan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.