Description

(4-Fluoro-3-(Methylsulfonyl)Phenyl)Boronic Acid is a high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its molecular structure, featuring both a fluorine substituent and a methylsulfonyl group, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of advanced intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for forming carbon-carbon bonds, enabling the synthesis of biaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Serves as a critical precursor in the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research & Development: Used in the creation of new herbicides and fungicides, leveraging the fluorine and sulfone motifs for enhanced biological activity and stability.
• Material Science & OLED Development: Employed in the synthesis of organic electronic materials, where the boronic acid functionality allows for precise molecular assembly.
• Chemical Biology & Probe Development: Acts as a handle for bioconjugation and the development of chemical probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP conditions.

Basic Information

Product Name	(4-Fluoro-3-(Methylsulfonyl)Phenyl)Boronic Acid
CAS No.	1268496-35-0
Molecular Formula	C7H8BFO4S
Molecular Weight	218.01 g/mol
Synonyms	4-Fluoro-3-(methylsulfonyl)benzeneboronic acid; [4-Fluoro-3-(methylsulfonyl)phenyl]boronic acid; 3-Methylsulfonyl-4-fluorophenylboronic acid; B-[4-Fluoro-3-(methylsulfonyl)phenyl]boronic acid; (4-Fluoro-3-methanesulfonylphenyl)boronic acid; 4-Fluoro-3-methanesulfonylbenzeneboronic acid; 1268496-35-0; 4-Fluoro-3-methylsulfonylphenylboronic acid
EINECS	Contact for details

Quality Control

Our (4-Fluoro-3-(Methylsulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.