Description

2-(2-Fluoro-Benzyl)-Succinic Acid is a specialized fluorinated organic acid building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a succinic acid core with a fluorinated benzyl group, offering a versatile handle for introducing both carboxylic acid functionality and fluorine atoms into target molecules. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis and separation sciences.
• Polymer Modification: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in organic synthesis, including C-C bond formation and fluorination chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fluorinated molecules for electronics, materials science, and diagnostics.

Basic Information

Product Name	2-(2-Fluoro-Benzyl)-Succinic Acid
CAS No.	1267298-84-9
Molecular Formula	C11H11FO4
Molecular Weight	226.20 g/mol
Synonyms	2-(2-Fluorobenzyl)butanedioic acid; Succinic acid, 2-(2-fluorobenzyl)-; 2-(2-Fluorophenylmethyl)succinic acid; 2-(2-Fluoro-benzyl)-succinic acid; (2-Fluorobenzyl)succinic acid; 1267298-84-9; Butanedioic acid, 2-[(2-fluorophenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Benzyl)-Succinic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure storage containers are made of compatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.