Description

n-(5-Bromopyridin-3-Yl)-3-Methylbutanamide is a high-purity, synthetic organic compound featuring a brominated pyridine core, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This product is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their discovery and scale-up programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the bioactivity of the bromopyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: A building block for organic electronic materials and functional polymers due to its aromatic and halogenated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific brominated intermediates.

Basic Information

Product Name	n-(5-Bromopyridin-3-Yl)-3-Methylbutanamide
CAS No.	1266227-13-7
Molecular Formula	C10H13BrN2O
Molecular Weight	257.13 g/mol
Synonyms	3-Methyl-N-(5-bromo-3-pyridinyl)butanamide; 5-Bromo-N-isobutylnicotinamide; 3-Methylbutanamide, N-(5-bromo-3-pyridinyl)-; N-(5-Bromopyridin-3-yl)-3-methylbutyramide; 1266227-13-7; 5-Bromo-3-pyridinyl isobutyl amide; Isobutyramide, N-(5-bromo-3-pyridyl)-
EINECS	Contact for details

Quality Control

Our n-(5-Bromopyridin-3-Yl)-3-Methylbutanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP standards and regulatory compliance (including REACH) ensures a reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.