Description

1-(4-Chloro-3-Fluorophenyl)Cyclopropane-1-Carbonitrile is a high-value, functionalized cyclopropane derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the creation of novel molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs) and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the fluorinated phenyl ring.
• Ligand & Catalyst Synthesis: Serves as a sophisticated scaffold for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its rigid cyclopropane structure.
• Chemical Biology Probes: Utilized as a core structure for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-(4-Chloro-3-Fluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	1265476-80-9
Molecular Formula	C10H7ClFN
Molecular Weight	195.62 g/mol
Synonyms	1-(4-Chloro-3-fluorophenyl)cyclopropanecarbonitrile; 4-Chloro-3-fluoro-α-(cyanomethyl)benzenemethanol, cyclic acetal with formaldehyde; (4-Chloro-3-fluorophenyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(4-chloro-3-fluorophenyl)-; 1-(4-Chloro-3-fluorophenyl)cyclopropane-1-carbonitrile; 1265476-80-9
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-3-Fluorophenyl)Cyclopropane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.