Description

3-Fluoropiperidine-3-Carbonitrile is a high-value, multi-functional heterocyclic building block featuring both a fluorine substituent and a nitrile group on the same carbon atom of the piperidine ring. This unique structure makes it a critical intermediate for medicinal chemistry and pharmaceutical research, enabling the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Building Block: Used to introduce both fluorinated and cyano-functionalized piperidine motifs into drug candidates to modulate potency, metabolic stability, and physicochemical properties.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides that require fluorinated heterocyclic cores.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating sophisticated chiral ligands and catalysts used in asymmetric synthesis.
• Advanced Material Precursor: Potential use in the development of specialty polymers and functional materials with tailored properties.

Basic Information

Product Name	3-Fluoropiperidine-3-Carbonitrile
CAS No.	1265323-71-4
Molecular Formula	C6H9FN2
Molecular Weight	128.15 g/mol
Synonyms	3-Fluoro-3-cyanopiperidine; 3-Fluoro-3-piperidinecarbonitrile; 3-Fluoro-3-cyano-piperidine; 3-Fluoropiperidine-3-carbonitrile; Piperidine-3-carbonitrile, 3-fluoro-; 3-Cyano-3-fluoropiperidine
EINECS	Contact for details

Quality Control

Our 3-Fluoropiperidine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.