Description

3,5-Difluoro-4-(1-Pyrrolidinylcarbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative designed for advanced synthetic chemistry applications. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily utilized by R&D scientists and process chemists in the life sciences sector for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed in the development of molecular probes and bioconjugates for diagnostic and research purposes.
• Catalyst Ligand Synthesis: Acts as a starting material for constructing novel ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API manufacturing.

Basic Information

Product Name	3,5-Difluoro-4-(1-Pyrrolidinylcarbonyl)Phenylboronic Acid
CAS No.	1264616-16-1
Molecular Formula	C11H12BF2NO3
Molecular Weight	255.03 g/mol
Synonyms	4-Borono-3,5-difluoro-N-pyrrolidin-1-ylbenzamide; [3,5-Difluoro-4-(pyrrolidine-1-carbonyl)phenyl]boronic acid; 3,5-Difluoro-4-(pyrrolidine-1-carbonyl)benzeneboronic acid; 4-(1-Pyrrolidinylcarbonyl)-3,5-difluorophenylboronic Acid; B-[3,5-Difluoro-4-(1-pyrrolidinylcarbonyl)phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(1-Pyrrolidinylcarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.