Description

2-(Benzyloxy)-4-Bromo-6-Fluorophenylboronic Acid CAS NO 1264175-59-8 is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing complex fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the introduction of specific halogenated aryl groups is required.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for catalysts or monomers for specialized polymers.
• Chemical Biology Probes: Serves as a building block for synthesizing molecular probes and tags used in biochemical and diagnostic applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development in cross-coupling chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	2-(Benzyloxy)-4-Bromo-6-Fluorophenylboronic Acid
CAS No.	1264175-59-8
Molecular Formula	C₁₃H₁₁BBrFO₃
Molecular Weight	340.94 g/mol
Synonyms	4-Bromo-2-(benzyloxy)-6-fluorophenylboronic acid; (4-Bromo-2-(benzyloxy)-6-fluorophenyl)boronic acid; 2-Benzyloxy-4-bromo-6-fluorobenzeneboronic acid; B-[4-Bromo-2-(phenylmethoxy)-6-fluorophenyl]boronic acid; 1264175-59-8; AKOS026710293; FT-0774837
EINECS	Contact for details

Quality Control

Our production of 2-(Benzyloxy)-4-Bromo-6-Fluorophenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (by HPLC). Each lot is fully characterized and undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.