Description

(5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyridine and fluorine motifs are common for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and functionalized pyridine derivatives.
• Ligand Synthesis: Can be utilized to create novel bidentate ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	(5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid
CAS No.	1264127-92-5
Molecular Formula	C11H15BFNO3
Molecular Weight	239.05 g/mol
Synonyms	4-Borono-5-fluoro-2-isopropoxypyridine; 2-Isopropoxy-5-fluoropyridine-4-boronic acid; (5-Fluoro-2-isopropoxy-4-pyridinyl)boronic acid; 5-Fluoro-2-isopropoxypyridine-4-boronic acid; 4-Pyridineboronic acid, 5-fluoro-2-(1-methylethoxy)-; B-(5-Fluoro-2-isopropoxypyridin-4-yl)boronic acid
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-Isopropoxypyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.