Description

2-(3,4-Difluorophenyl)Acetimidamide Hydrochloride is a high-purity, synthetically valuable organic intermediate characterized by its acetimidamide hydrochloride functional group and difluorinated aromatic ring. This compound is of significant commercial interest due to its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the difluorophenyl moiety.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or reagent in the development of chemical probes and enzyme inhibitors for target validation studies.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials where fluorinated aromatic units enhance stability and performance.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	2-(3,4-Difluorophenyl)Acetimidamide Hydrochloride
CAS No.	1263285-11-5
Molecular Formula	C8H9ClF2N2
Molecular Weight	206.62 g/mol
Synonyms	2-(3,4-Difluorophenyl)ethanimidamide hydrochloride; 3,4-Difluoro-α-(aminoiminomethyl)benzenemethanol hydrochloride; Acetimidamide, 2-(3,4-difluorophenyl)-, hydrochloride; 2-(3,4-Difluorophenyl)-1-iminoethylamine hydrochloride; (3,4-Difluorophenyl)acetimidamide HCl; 1263285-11-5; 2-(3,4-Difluorophenyl)acetamidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorophenyl)Acetimidamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For advanced applications, we support development under cGMP guidelines and can tailor purity grades to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.