Description

2-Butanamine, 1,1,1-Trifluoro-3-Methyl-, Hydrochloride (1:1) is a high-purity, fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. Its value lies in its unique trifluoromethyl group, which is critical for modulating the lipophilicity, metabolic stability, and bioavailability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and advanced materials where fluorinated groups impart unique chemical resistance and surface properties.
• Fluorine Chemistry Library Building: A valuable reagent for constructing diverse compound libraries in drug discovery, facilitating structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Butanamine, 1,1,1-Trifluoro-3-Methyl-, Hydrochloride (1:1)
CAS No.	1263282-44-5
Molecular Formula	C5H10F3N • HCl
Molecular Weight	177.60 g/mol
Synonyms	1,1,1-Trifluoro-3-methyl-2-butanamine hydrochloride; 3-Methyl-1,1,1-trifluoro-2-butanamine hydrochloride; 1,1,1-Trifluoro-3-methylbutan-2-amine hydrochloride; (RS)-1,1,1-Trifluoro-3-methylbutan-2-amine hydrochloride; (±)-1,1,1-Trifluoro-3-methyl-2-butanamine hydrochloride; rac-1,1,1-Trifluoro-3-methylbutan-2-amine hydrochloride; 2-Amino-1,1,1-trifluoro-3-methylbutane hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Butanamine, 1,1,1-Trifluoro-3-Methyl-, Hydrochloride (1:1) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.