Description

(1-Trityl-Aziridin-2-Yl)-Acetonitrile is a specialized, high-purity organic building block featuring a protected aziridine ring. This compound matters for its role as a key chiral intermediate in the synthesis of complex, biologically active molecules, enabling precise stereochemical control. Pharmaceutical researchers and fine chemical manufacturers need it for developing advanced drug candidates, particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of protease inhibitors and other antiviral compounds.
• Oncology Therapeutics: Serves as a building block for targeted cancer therapies and kinase inhibitors.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct complex molecular architectures.
• Peptidomimetics Development: Integral for creating stable, bioavailable peptide analogs.
• Agrochemical Research: Used in the synthesis of advanced, chiral crop protection agents.
• Academic & Process Chemistry: A valuable reagent for methodological development and scale-up studies in organic chemistry.

Basic Information

Product Name	(1-Trityl-Aziridin-2-Yl)-Acetonitrile
CAS No.	1263279-81-7
Molecular Formula	C25H22N2
Molecular Weight	350.46 g/mol
Synonyms	2-[(Triphenylmethyl)aziridin-1-yl]acetonitrile; 1-Tritylaziridine-2-acetonitrile; (1-Trityl-2-aziridinyl)acetonitrile; 2-(1-Tritylaziridin-2-yl)acetonitrile; N-Tritylaziridine-2-acetonitrile; Aziridine-2-acetonitrile, 1-trityl-; Triphenylmethylaziridinylacetonitrile
EINECS	Contact for details

Quality Control

Our (1-Trityl-Aziridin-2-Yl)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.