Description

Bcn-Oh CAS NO 1263166-90-0 is a high-purity chemical intermediate, specifically a functionalized bicyclo[6.1.0]nonane derivative, valued for its unique strained-ring structure and reactive hydroxyl group. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures with high precision. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, chemical biology, and the development of novel therapeutics and materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in fragment-based drug discovery.
• Chemical Biology Probe Development: Used for the synthesis of activity-based probes (ABPs) and other chemical tools to study enzyme function and biological pathways.
• Advanced Material Synthesis: Acts as a precursor for polymers and specialty materials that require rigid, three-dimensional structural components.
• Cross-Coupling Reactions: The functional handle facilitates participation in various metal-catalyzed cross-coupling reactions for C-C and C-X bond formation.
• Bioconjugation Chemistry: Utilized in the development of linkers and reagents for protein labeling and antibody-drug conjugate (ADC) research.
• Academic & Industrial R&D: Employed in exploratory research for developing new synthetic methodologies and novel compound libraries.

Basic Information

Item	Detail
Product Name	Bcn-Oh
CAS No.	1263166-90-0
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol; Bicyclo[6.1.0]non-4-yn-9-ylmethanol; BCN-OH; BCN alcohol; (1R,8S,9s)-BCN-OH; Bicyclononyne-OH; DBCO precursor alcohol; Strain-promoted alkyne precursor
EINECS	Contact for details

Quality Control

Our Bcn-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.