Description

(2R)-4-[(2,4-Dinitrophenyl)Amino]-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Butanoic Acid is a sophisticated chiral amino acid derivative, engineered for advanced research and development in organic synthesis. This compound is a critical Fmoc-protected building block, valued for its role in constructing complex peptide and peptidomimetic structures with high stereochemical fidelity. It is essential for scientists in pharmaceutical R&D and academic research focused on developing novel bioactive molecules and therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key chiral intermediate for the controlled incorporation of modified amino acids into peptide chains.
• Pharmaceutical Research: Building block for the synthesis of potential drug candidates, particularly in oncology and metabolic disease research.
• Peptidomimetic Development: Used to create non-natural peptide analogs with enhanced stability and biological activity.
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for studying protein-protein interactions and enzyme mechanisms.
• Academic & Industrial R&D: Fundamental research tool in synthetic organic chemistry and medicinal chemistry laboratories.
• Custom Synthesis Services: A high-value starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis.

Basic Information

Product Name	(2R)-4-[(2,4-Dinitrophenyl)Amino]-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Butanoic Acid
CAS No.	1263047-25-1
Molecular Formula	C25H22N4O8
Molecular Weight	506.47 g/mol
Synonyms	Fmoc-D-Dap(Dnp)-OH; (2R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((2,4-dinitrophenyl)amino)butanoic acid; Fmoc-D-2,4-dinitrophenylornithine; Nδ-Dnp-D-ornithine, Nα-Fmoc derivative; Fmoc-D-Dap(Dnp)-OH; D-Dap(Dnp)-OH, Fmoc-; Fmoc-D-4-amino-2-((2,4-dinitrophenyl)amino)butanoic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep under inert atmosphere for long-term storage to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.