Description

Boc-Dap(Dde)-Oh CAS NO 1263045-09-5 is a specialized, orthogonally protected amino acid derivative used in advanced peptide synthesis. This compound is critical for enabling complex, multi-step solid-phase peptide synthesis (SPPS) strategies by providing selective deprotection pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel peptide therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of complex peptides, particularly those requiring branched or modified structures.
• Orthogonal Protection Strategy: Enables the selective removal of the Dde protecting group in the presence of acid-labile Boc and base-labile Fmoc groups, facilitating sophisticated synthetic routes.
• Peptide Drug Discovery: Used in the research and development of peptide-based pharmaceuticals, including hormone analogs and targeted drug conjugates.
• Bioconjugation and Labeling: Serves as a precursor for introducing specific functional handles or fluorescent labels into peptides at defined positions.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic and Industrial R&D: A vital reagent for fundamental research in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Boc-Dap(Dde)-Oh
CAS No.	1263045-09-5
Molecular Formula	C₂₀H₃₁N₃O₇
Molecular Weight	425.48 g/mol
Synonyms	Boc-D-2,3-diaminopropionic acid(Dde)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethylamino)propanoic acid; N-α-Boc-N-β-Dde-D-2,3-diaminopropionic Acid; Boc-D-Dap(Dde)-OH; Fmoc-D-Dap(Dde)-OH (common related compound); N-(tert-Butoxycarbonyl)-N'-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)-D-2,3-diaminopropanoic Acid; Orthogonally Protected D-Diaminopropionic Acid Derivative
EINECS	Contact for details

Quality Control

Our Boc-Dap(Dde)-Oh is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is analyzed by HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.