Description

Fmoc-(S)-2-Aminononanoic Acid CAS NO 1262886-65-6 is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amino group. This compound is a critical chiral building block for the solid-phase peptide synthesis (SPPS) of peptides and peptidomimetics, enabling the precise incorporation of a hydrophobic side chain. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and CROs engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key monomer for the automated synthesis of custom peptides containing non-natural amino acid residues.
• Pharmaceutical Research: For the development and production of novel peptide-based drug candidates, including antimicrobial peptides and hormone analogs.
• Peptidomimetic Design: Used to introduce specific structural features, such as increased lipophilicity or conformational constraints, into peptide backbones.
• Bioconjugation & Probe Synthesis: Serves as a precursor for creating labeled peptides or peptide-conjugates for diagnostic and imaging applications.
• Academic & Industrial R&D: Employed in biochemical research to study protein-protein interactions, enzyme substrates, and receptor ligands.

Basic Information

Product Name	Fmoc-(S)-2-Aminononanoic Acid
CAS No.	1262886-65-6
Molecular Formula	C₂₄H₂₉NO₄
Molecular Weight	395.49 g/mol
Synonyms	Fmoc-(S)-2-Aminononanoic Acid; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)nonanoic acid; Fmoc-Norleucine analog; Fmoc-2-Aminononanoic Acid; N-α-Fmoc-(S)-2-Aminononanoic Acid; Fmoc-S-2-AAN-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-2-aminononanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-2-Aminononanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.