Description

Fmoc-(R)-2-Amino-3-Cyclopentylpropanoic Acid CAS NO 1262802-59-4 is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a cyclopentyl side chain. This compound is essential for the solid-phase peptide synthesis (SPPS) of complex peptides and peptidomimetics, where it introduces structural constraints and lipophilicity. It is a critical building block for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science.

Application

• Pharmaceutical Peptide Synthesis: A key intermediate for constructing therapeutic peptides with enhanced metabolic stability and membrane permeability.
• Peptidomimetic Drug Discovery: Used to introduce cyclopentyl groups into scaffold designs, modulating bioactivity and receptor selectivity.
• Agrochemical Active Ingredients: Employed in the research and development of novel peptide-based pesticides and fungicides.
• Bioconjugation and Probe Development: Serves as a modified amino acid for creating labeled peptides for diagnostic and imaging applications.
• Academic & Industrial R&D: A fundamental reagent for studying protein-protein interactions and structure-activity relationships (SAR).
• Custom Peptide Service Providers: A standard inventory item for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Fmoc-(R)-2-Amino-3-Cyclopentylpropanoic Acid
CAS No.	1262802-59-4
Molecular Formula	C₂₃H₂₅NO₄
Molecular Weight	379.45 g/mol
Synonyms	Fmoc-(R)-3-Cyclopentylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-cyclopentyl-D-alanine; Fmoc-D-3-Cyclopentyl-Ala-OH; Fmoc-D-Cpa-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclopentylpropanoic acid; N-α-Fmoc-D-3-cyclopentylalanine; Fmoc-D-Cyclopentylalanine; N-Fmoc-D-3-cyclopentylalanine
EINECS	Contact for details

Quality Control

Our Fmoc-(R)-2-Amino-3-Cyclopentylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.