Description

Cefozopran Dihydrochloride is a fourth-generation cephalosporin antibiotic intermediate, specifically designed for enhanced stability and broad-spectrum antibacterial activity. Its value lies in its critical role as a high-purity building block for the synthesis of advanced pharmaceutical formulations targeting resistant bacterial infections. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries engaged in the research, development, and production of next-generation injectable antibiotics.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API) Synthesis: Primary use as a key intermediate in the manufacturing of Cefozopran and related cephalosporin antibiotic drugs.
• Research & Development: Serves as a critical reference standard and starting material in antimicrobial research programs within academic and industrial laboratories.
• Formulation Development: Used in the development of stable, injectable dosage forms requiring high-purity antibiotic components.
• Fine Chemical Production: Employed in multi-step organic synthesis for creating novel β-lactam derivatives and exploring new antibacterial agents.

Basic Information

Product Name	Cefozopran Dihydrochloride
CAS No.	1262200-57-6
Molecular Formula	C₂₀H₂₈Cl₂N₈O₇S₂
Molecular Weight	627.51 g/mol
Synonyms	(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[[(5-methyl-2H-tetrazol-2-yl)methyl]thio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride; SC-004 Dihydrochloride; SCE-2787 Dihydrochloride; Cefozopran HCl; (6R,7R)-7-[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[[(5-methyl-2H-tetrazol-2-yl)methyl]thio]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our Cefozopran Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents, ensuring it meets exacting standards for pharmaceutical intermediate use. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.