Description

Mucopolysaccharidosis Type II Related Compound MPS-II-3 (IDS-IS) is a high-purity reference standard and biochemical reagent critical for research and development in the life sciences. This compound is essential for the study of Hunter Syndrome (Mucopolysaccharidosis Type II), enabling accurate analytical method development, quality control, and diagnostic assay validation. It serves as a vital tool for pharmaceutical companies, clinical research organizations, and academic institutions focused on lysosomal storage disorders and therapeutic development.

Application

• Analytical Reference Standard: Primary use as a certified reference material for the identification and quantification of Iduronate 2-sulfatase (IDS) enzyme activity and related metabolites in biological samples.
• Biochemical Research: Investigation of the pathophysiology of Mucopolysaccharidosis Type II (Hunter Syndrome) and the biochemical pathways involving glycosaminoglycan metabolism.
• Diagnostic Development: Calibration and validation of diagnostic kits, immunoassays, and mass spectrometry-based methods for the detection of MPS-II biomarkers.
• Pharmaceutical QC/QA: In-process testing and final release analysis for enzyme replacement therapies (ERTs) and other novel treatments targeting Hunter Syndrome.
• Metabolite Studies: Used in studies to understand the accumulation and clearance of specific metabolites in disease models.
• Method Development & Validation: Serves as a critical component for developing and validating HPLC, LC-MS/MS, and other chromatographic methods in regulated laboratories.

Basic Information

Product Name	Mucopolysaccharidosis Type II Related Compound MPS-II-3 (IDS-IS)
CAS No.	1262147-39-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IDS-IS; MPS-II-3; Iduronate 2-sulfatase Internal Standard; Hunter Syndrome Related Compound 3; MPS II Related Compound; 1262147-39-6; Ids-Is Reference Standard; Mucopolysaccharidosis Type II Biomarker
EINECS	Contact for details

Quality Control

Every batch of Mucopolysaccharidosis Type II Related Compound MPS-II-3 (IDS-IS) is manufactured and analyzed under strict quality systems. Our products undergo rigorous identity, purity, and stability testing to ensure compliance with the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results for purity, assay, and related substances analysis performed via validated methods such as HPLC and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label or Certificate of Analysis. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Assay (HPLC)	95.0% - 105.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.