Description

Phosphine, Dicyclohexyl[3,6-Dimethoxy-2',6'-Bis(1-Methylethyl)[1,1'-Biphenyl]-2-Yl]- is a specialized, high-value organophosphorus ligand used in advanced catalytic processes. Its primary value lies in enabling highly efficient and selective cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction stereochemistry and yield.

Application

• Catalyst Ligand for Cross-Coupling Reactions: A key component in Buchwald-Hartwig amination, Suzuki-Miyaura, and related C-C/C-N bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enables the production of complex, chiral active pharmaceutical ingredients (APIs) and key intermediates.
• Agrochemical Manufacturing: Used in the synthesis of novel, high-performance herbicides, fungicides, and insecticides.
• Materials Science Research: Facilitates the development of organic electronic materials, such as OLEDs and conductive polymers.
• Asymmetric Catalysis: Employed in reactions requiring high enantioselectivity for the production of single-isomer compounds.
• Academic and Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	Phosphine, Dicyclohexyl[3,6-Dimethoxy-2',6'-Bis(1-Methylethyl)[1,1'-Biphenyl]-2-Yl]-
CAS No.	1262046-23-0
Molecular Formula	C34H45O2P
Molecular Weight	516.70 g/mol
Synonyms	Dicyclohexyl(3,6-dimethoxy-2',6'-diisopropyl-[1,1'-biphenyl]-2-yl)phosphine; BrettPhos; RuPhos Precursor Ligand; 2'-(Dicyclohexylphosphino)-3,6-dimethoxy-2,4,6-triisopropyl-1,1'-biphenyl; CgPh-PCy2; Buchwald Ligand; Biarylphosphine Ligand
EINECS	Contact for details

Quality Control

Every batch of Phosphine, Dicyclohexyl[3,6-Dimethoxy-2',6'-Bis(1-Methylethyl)[1,1'-Biphenyl]-2-Yl]- is manufactured and tested under strict quality management systems to ensure high purity, consistency, and performance in sensitive catalytic applications. Our standard grade meets typical R&D and process development requirements, with comprehensive analysis via NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or humidity should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.