Description

8-(Trifluoromethoxy)Quinolin-3-Ol is a high-value, fluorinated quinoline derivative that serves as a critical synthetic intermediate in advanced chemical research and development. This compound is prized for its unique molecular scaffold, which combines the quinoline core with a trifluoromethoxy substituent, imparting desirable properties for creating novel materials and active compounds. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targets in oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the stability and bioactivity of the fluorinated quinoline structure.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe: Utilized as a core structure for developing fluorescent probes or enzyme inhibitors for biochemical assays.
• Custom Synthesis & Scale-up: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.

Basic Information

Product Name	8-(Trifluoromethoxy)Quinolin-3-Ol
CAS No.	1261886-64-9
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	3-Hydroxy-8-(trifluoromethoxy)quinoline; 8-(Trifluoromethoxy)-3-quinolinol; 8-Trifluoromethoxyquinolin-3-ol; Quinolin-3-ol, 8-(trifluoromethoxy)-; 1261886-64-9
EINECS	Contact for details

Quality Control

Every batch of 8-(Trifluoromethoxy)Quinolin-3-Ol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.