Description

2-(3-Fluoro-4-Iodophenyl)Acetic Acid is a high-purity fluorinated and iodinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its unique bifunctional halogenated structure, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and as a key intermediate in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated phenylacetic acid structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of the iodine atom.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.
• Academic & Industrial R&D: Essential for method development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	2-(3-Fluoro-4-Iodophenyl)Acetic Acid
CAS No.	1261874-58-1
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	(3-Fluoro-4-iodophenyl)acetic acid; 2-(3-Fluoro-4-iodophenyl)ethanoic acid; 4-Iodo-3-fluorobenzeneacetic acid; 2-(4-Iodo-3-fluorophenyl)acetic acid; α-(3-Fluoro-4-iodophenyl)acetic acid; 3-Fluoro-4-iodobenzeneacetic acid; NSC 864065; FIPA
EINECS	Contact for details

Quality Control

Our production of 2-(3-Fluoro-4-Iodophenyl)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.