Description

Benzeneacetic Acid, 5-Fluoro-2-Iodo- is a high-purity, halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and iodinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the halogen atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for incorporating halogen tags into biomolecules for imaging, binding studies, and proteomics research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific halogenated intermediates.

Basic Information

Product Name	Benzeneacetic Acid, 5-Fluoro-2-Iodo-
CAS No.	1261862-94-5
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	2-Iodo-5-fluorophenylacetic acid; (5-Fluoro-2-iodophenyl)acetic acid; 5-Fluoro-2-iodobenzeneacetic acid; α-(5-Fluoro-2-iodophenyl)acetic acid; 2-(5-Fluoro-2-iodophenyl)acetic acid; 5-Fluoro-2-iodo-α-toluic acid; 5-Fluoro-2-iodohomobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetic Acid, 5-Fluoro-2-Iodo- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. Due to its light-sensitive nature, containers should be kept in secondary packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.